Protein Domain : Poly(ADP-ribose) polymerase, regulatory domain IPR004102

Type  Domain
Description  Poly(ADP-ribose) polymerase catalyses the covalent attachment of ADP-ribose units from NAD+ to itself and to a limited number of other DNA binding proteins, which decreases their affinity for DNA. Poly(ADP-ribose) polymerase is a regulatory component induced by DNA damage. The regulatory domain of the polymerase is almost always associated with the C-terminal catalytic domain (see ). This domain consists of a duplication of two helix-loop-helix structural repeats [ ].
Short Name  Poly(ADP-ribose)pol_reg_dom
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0 Child Features

2 Gene Families

Trail: ProteinDomain

319 Genes

Trail: ProteinDomain

1 Ontology Annotations

Trail: ProteinDomain

0 Parent Features

14 Publications

Trail: ProteinDomain
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