Ontology Term : Pfam:PF08267 Cobalamin-independent synthase, N-terminal domain EMBL-EBI

Description  The N-terminal domain and C-terminal domains of cobalamin-independent synthases together define a catalytic cleft in the enzyme. The N-terminal domain is thought to bind the substrate, in particular, the negatively charged polyglutamate chain. The N-terminal domain is also thought to stabilise a loop from the C-terminal domain [1].
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