GO Term : GO:0005852 eukaryotic translation initiation factor 3 complex Gene Ontology

Description  A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs.
Namespace  cellular_component
Obsolete  false

58 Data Sets

Trail: GOTerm

1 Ontology

Trail: GOTerm

1316 Ontology Annotations

Trail: GOTerm

6 Parents

Trail: GOTerm

8 Relations

Trail: GOTerm

2 Synonyms

Trail: GOTerm
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