GO Term : GO:0003714 transcription corepressor activity Gene Ontology

Description  A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.
Namespace  molecular_function
Obsolete  false

57 Data Sets

Trail: GOTerm

1 Ontology

Trail: GOTerm

597 Ontology Annotations

Trail: GOTerm

4 Parents

Trail: GOTerm

4 Relations

Trail: GOTerm

5 Synonyms

Trail: GOTerm
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