Protein Domain : SAICAR synthetase, conserved site IPR018236

Type  Conserved_site
Description  Phosphoribosylaminoimidazole-succinocarboxamide synthase ( ) (SAICAR synthetase) catalyses the seventh step in the de novopurine biosynthetic pathway; the ATP-dependent conversion of 5'-phosphoribosyl-5-aminoimidazole-4-carboxylic acid and aspartic acid to SAICAR [ , ].In bacteria (purC), fungi (ADE1) and plants (Pur7), SAICAR synthetase is a monofunctional protein; in animals it is the N-terminal domain of a bifunctional enzyme that also catalyse phosphoribosylaminoimidazole carboxylase (AIRC) activity (see ).
Short Name  SAICAR_synthetase_CS
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0 Child Features

0 Gene Families

113 Genes

Trail: ProteinDomain

2 Ontology Annotations

Trail: ProteinDomain

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13 Publications

Trail: ProteinDomain
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