Protein Domain : Alpha-2-glucosyltransferase Alg10 IPR016900

Type  Family
Description  Alg10 (asparagine-linked glycosylation) ( ) is a dolichyl-phosphoglucose-dependent glucosyltransferase which adds the terminal alpha-1,2 glucose to the lipid-linked Glc2Man9GlcNAc2 oligosaccharide. The terminal alpha-1,2-linked glucose residue is important for substrate recognition by the oligosaccharyltransferase [ ]. In Saccharomyces cerevisiae, Alg10 has a role in regulation of the expression of a myo-inositol transporter, Itr1 (hence the name Die2, standing for derepression of Itr1 expression) []. It also regulates the expression of Ino1, which is an inositol-3-phosphate synthase []. Alg10 is homologous to human and rat potassium channel regulatory protein KCR1, which diminishes the cardiac repolarising current I(Kr) drug response [, ].
Short Name  Alg10

0 Child Features

1 Gene Families

123 Genes

2 Ontology Annotations

0 Parent Features

14 Publications

USDA
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