Ontology Term : Pfam:PF12220 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal EMBL-EBI

Description  This domain is found in eukaryotes. This domain is about 90 amino acids in length. This domain is found associated with Pfam:PF00076. This domain is part of U1 snRNP, which is the pre-mRNA binding protein of the penta-snRNP spliceosome complex. It extends over a distance of 180 A from its RNA binding domain, wraps around the core domain of U1 snRNP consisting of the seven Sm proteins and finally contacts U1-C, which is crucial for 5'-splice-site recognition.
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271 Ontology Annotations

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