v5.1.0.3
Glycine data from LIS
Type | Domain |
Description | Exportin-2, also known as CAS, is an export receptor for importin-alpha [ ]. It binds strongly to importin alpha only in the presence of RanGTP, forming an importin alpha/CAS/RanGTP complex. Exportin-2 mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates have been released into the nucleoplasm [].This entry represents the C-terminal domain of XPO2. Structural studies of its yeast homologue, Cse1, indicate that this domain binds to both the transport-orchestrating protein RanGTP and the cargo molecule that is being exported [ ]. |
Short Name | XPO2_C |