Protein Domain : WIBG, Mago-binding IPR015362

Type  Domain
Description  Partner of Y14 and mago (PYM, also known as WIBG) is a key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmarks for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation [ , ].The N-terminal domain of PYM adopts a small globular all-beta-domain structure, with a three-stranded β-sheet and a contiguous β-hairpin. It binds to both Mago and Y14 [ ].
Short Name  WIBG_mago-bd
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0 Child Features

1 Gene Families

Trail: ProteinDomain

154 Genes

Trail: ProteinDomain

0 Ontology Annotations

0 Parent Features

14 Publications

Trail: ProteinDomain
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