Protein Domain : Porin, eukaryotic type IPR001925

Type  Family
Description  Eukaryotic mitochondrial porins are voltage-dependent anion-selective channels (VDAC) that behave as general diffusion pores for small hydrophilic molecules [ , , , ]. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV.The proteins are composed of between 12 to 16 β-strands that span the mitochondrial outer membrane. Yeast contains two members of this family (genes POR1 and POR2); vertebrates have at least three members (genes VDAC1, VDAC2 and VDAC3) [ , ].
Short Name  Porin_Euk
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0 Child Features

0 Gene Families

364 Genes

Trail: ProteinDomain

3 Ontology Annotations

Trail: ProteinDomain

1 Parent Features

Trail: ProteinDomain

13 Publications

Trail: ProteinDomain
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