Protein Domain : Replication factor-A protein 1, N-terminal IPR007199

Type  Domain
Description  Replication factor-a protein 1 (RPA1) forms a multiprotein complex with RPA2 and RPA3 that binds single-stranded DNA and functions in the recognition of DNA damage for nucleotide excision repair. The complex binds to single-stranded DNA sequences participating in DNA replication in addition to those mediating transcriptional repression and activation, and stimulates the activity of cognate strand exchange protein Sep1. It cooperates with T-AG and DNA topoisomerase I to unwind template DNA containing the Simian Virus 40 origin of replication [ ].
Short Name  Rep_factor-A_N
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0 Child Features

0 Gene Families

253 Genes

Trail: ProteinDomain

3 Ontology Annotations

Trail: ProteinDomain

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13 Publications

Trail: ProteinDomain
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