LIS - Legume Information System
Information about legume traits for crop improvement
GlycineMine
v5.1.0.3
Glycine data from LIS
v5.1.0.3
Glycine data from LIS
| Type | Family |
| Description | A variety of substrate carrier proteins that are involved in energy transfer are found in the inner mitochondrial membrane [ , , , , ]. Such proteins include: ADP,ATP carrier protein (ADP/ATP translocase); 2-oxoglutarate/malate carrier protein; phosphate carrier protein; tricarboxylate transport protein (or citrate transport protein); Graves disease carrier protein; yeast mitochondrial proteins MRS3 and MRS4; yeast mitochondrial FAD carrier protein; and many others.Sequence analysis of selected members of the carrier protein family has suggested the presence of six transmembrane (TM) domains, with varying degrees of sequence conservation and hydrophilicity []. The TM regions, and adjacent hydrophilic loops, are more highly conserved than other regions of the proteins []. All members of the family appear to consist of a tripartite structure, each of the repeated segments being ~100 residues in length []. Each repeat contains two TM domains, the first being morehydrophobic, with conserved glycyl and prolyl residues. Five of the six TM domains are followed by the conserved sequence (D/E)-Hy(K/R), where - denotes any residue and Hy is a hydrophobic position [ ].Mitochondrial ADP/ATP translocase, an abundant component of the inner membrane, carries ATP from the matrix into the inter-membrane space and transports ADP back [ , ]. The protein is an integral membrane protein that functions as a homodimer.Mutations of the human ADP/ATP translocase 1 (also known as SLC25A4) gene cause mitochondrial diseases, such as PEOA2 and MTDPS12B [ ]. This family contains proteins found in eucaryotes. |
| Short Name | ADT_euk_type |
