Protein Domain : Small EDRK-rich factor-like, N-terminal IPR007513

Type  Domain
Description  This entry represents the N-terminal domain of Small EDRK-rich factors (SERFs), including SERF1/2 from human. Proteins containing this domain are short proteins that are rich in aspartate, glutamate, lysine and arginine [ ]. SERF1/2 are positive regulators of amyloid protein aggregation and proteotoxicity; they induce conformational changes in amyloid proteins, driving them into compact formations preceding the formation of aggregates [, , ].
Short Name  SERF-like_N
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0 Child Features

1 Gene Families

Trail: ProteinDomain

247 Genes

Trail: ProteinDomain

0 Ontology Annotations

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14 Publications

Trail: ProteinDomain
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