Protein Domain : Nucleoside-triphosphatase, THEP1 type IPR004948

Type  Family
Description  This entry represents a family of nucleoside-triphosphatases which have activity towards ATP, GTP, CTP, TTP and UTP and may hydrolyse nucleoside diphosphates with lower efficiency [ ]. It includes proteins from bacteria to human, and the function was determined first in a hyperthermophilic bacterium to be an NTPase []. The structure of one member-sequence represents a variation of the RecA fold, and implies that the function might be that of a DNA/RNA modifying enzyme []. The sequence carries both a Walker A and Walker B motif which together are characteristic of ATPases or GTPases. The protein exhibits an increased expression profile in human liver cholangiocarcinoma when compared to normal tissue [].
Short Name  Nuc-triphosphatase_THEP1

0 Child Features

1 Gene Families

84 Genes

1 Ontology Annotations

0 Parent Features

14 Publications

USDA
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