Protein Domain : SIT4 phosphatase-associated protein family IPR007587

Type  Family
Description  This entry includes budding yeast Sit4-associated proteins, such as Sap155, Sap185, and Sap190. Sit4 is a phosphatase involved in a variety of processes including transcription, translation, bud formation, glycogen metabolism, monovalent ion homeostasis, H+ transport, and telomere function [ ]. This entry also includes mammalian PP6 (Sit4 homologue)-associated proteins, such as PP6R1, PP6R2, and PP6R3 [ ]. They are regulatory subunits of PP6 involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha [].
Short Name  SAPS

0 Child Features

3 Gene Families

363 Genes

2 Ontology Annotations

0 Parent Features

14 Publications

USDA
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