Protein Domain : Vesicle-associated membrane-protein-associated protein IPR016763

Type  Family
Description  This entry represents a family of vesicle-associated membrane-protein-associated proteins (VAPs) and plant VAP homologs (PVAPs) [ ]. VAPs (VAPA and VAPB in humans, VAPA, VAPB and VAPC in other mammals []) are endoplasmic reticulum (ER) proteins that play roles in vesicle trafficking, neurotransmitter release, microtubule organisation, lipid transport and unfolded protein response []. VAP proteins contain an MSP domain in their N-terminal half, which has been shown to interact with proteins containing a FFAT motif, such as members of the oxysterol-binding protein (OSBP) family or the phosphatidylinositol transfer proteins from the PITPNM family []. Yeast VAP homologues are known as Scs2 and Scs22 [].
Short Name  VAP

0 Child Features

4 Gene Families

656 Genes

1 Ontology Annotations

0 Parent Features

14 Publications

USDA
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