Protein Domain : SSRP1, dimerization domain IPR024954

Type  Domain
Description  This is the dimerization domain found in structure-specific recognition protein SSRP1 (POB3 in yeast) and related proteins, which are components of the FACT complex - a general chromatin factor that acts to reorganise nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair [ , , , ]. During transcription elongation the FACT complex acts as a histone chaperone that both destabilises and restores nucleosomal structure [, ].This domain has a Pleckstrin homology fold, made of 6 β-strands.
Short Name  SSRP1_DD

0 Child Features

1 Gene Families

169 Genes

0 Ontology Annotations

0 Parent Features

14 Publications

USDA
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