v5.1.0.3
Glycine data from LIS
Type | Domain |
Description | This is the dimerization domain found in structure-specific recognition protein SSRP1 (POB3 in yeast) and related proteins, which are components of the FACT complex - a general chromatin factor that acts to reorganise nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair [ , , , ]. During transcription elongation the FACT complex acts as a histone chaperone that both destabilises and restores nucleosomal structure [, ].This domain has a Pleckstrin homology fold, made of 6 β-strands. |
Short Name | SSRP1_DD |