Protein Domain : Ku, C-terminal IPR014893

Type  Domain
Description  The non-homologous end joining (NHEJ) pathway is one method by which double stranded breaks in chromosomal DNA are repaired. Ku is a component of a multi-protein complex that is involved in the NHEJ. Ku has affinity for DNA ends and recruits the DNA-dependent protein kinase catalytic subunit (DNA-PKcs). Ku also binds RNA, mediating the assembly of DNA-PKcs which has a role in ribosomal RNA biogenesis [ ]. This domain is found at the C-terminal of Ku which binds to DNA-PKcs [].
Short Name  Ku_PK_bind

0 Child Features

1 Gene Families

109 Genes

0 Ontology Annotations

0 Parent Features

14 Publications

USDA
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