LIS - Legume Information System
Information about legume traits for crop improvement
GlycineMine
v5.1.0.3
Glycine data from LIS
v5.1.0.3
Glycine data from LIS
| Type | Domain |
| Description | This entry represents the N-terminal domain found in the CAZyme GH116 family members, which presently includes enzymes with beta-glucosidase ( ), beta-xylosidase ( ) , and glucocerebrosidase ( ) activity [ , ]. The N-terminal is thought to be the luminal domain while the C-terminal is the cytosolic domain.Proteins containing this domain include animal non-lysosomal glucosylceramidase GBA2, which catalyse the conversion of glucosylceramide to free glucose and ceramide [ ]. GBA2 is involved in sphingomyelin generation and prevention of glycolipid accumulation and may also catalyse the hydrolysis of bile acid 3-O-glucosides, however, the relevance of such activity is unclear in vivo []. Mutations in the human protein cause motor-neurone defects in hereditary spastic paraplegia []. |
| Short Name | GH116_N |
