v5.1.0.3
Glycine data from LIS
Type | Homologous_superfamily |
Description | This superfamily represents a structural domain found in mitochondrial carrier proteins. Six α-helices form a compact transmembrane domain, which, at the surface towards the space between inner and outer mitochondrial membranes, reveals a deep depression. The structure suggests that transport substrates bind to the bottom of the cavity and that translocation results from a transition from a 'pit' to a 'channel' conformation [ ]. |
Short Name | Mt_carrier_dom_sf |