Protein Domain : Heavy metal-associated domain, copper ion-binding IPR006122

Type  Domain
Description  Proteins that transport heavy metals in micro-organisms and eukaryotes share similarities in their sequences and structures.These proteins provide an important focus for research, some being involved in bacterial resistance to toxic metals, such as lead and cadmium, while others are involved in inherited human syndromes, such as Wilson's and Menke's diseases [ ]. A conserved 30-residue domain has been found in a number of these heavy metal transport or detoxification proteins [ ]. The domain, which has been termed Heavy-Metal-Associated (HMA), contains two conserved cysteines that are probably involved in metal binding. This sub-domain is found in copper-binding proteins.
Short Name  HMA_Cu_ion-bd
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0 Child Features

0 Gene Families

492 Genes

Trail: ProteinDomain

1 Ontology Annotations

Trail: ProteinDomain

1 Parent Features

Trail: ProteinDomain

13 Publications

Trail: ProteinDomain
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