Ontology Term : Pfam:PF09405 CASC3/Barentsz eIF4AIII binding EMBL-EBI

Description  This domain is found on CASC3 (cancer susceptibility candidate gene 3 protein) which is also known as Barentsz (Btz). CASC3 is a component of the EJC (exon junction complex) which is a complex that is involved in post-transcriptional regulation of mRNA in metazoa. The complex is formed by the association of four proteins (eIF4AIII, Barentsz, Mago, and Y14), mRNA, and ATP. This domain wraps around eIF4AIII and stacks against the 5' nucleotide [1][2].
Namespace  Domain

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56 Data Sets

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1 Ontology

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