Protein Domain : RINT-1/Tip20 IPR007528

Type  Family
Description  This entry includes RINT-1 from animals, Tip20 from yeasts and MAIGO2 (Mag2) from plants. They play a role in anterograde transport from the endoplasmic reticulum (ER) to the Golgi and/or retrograde transport from the Golgi to the ER share sequence similarity [ ]. They are part of the CATCHR (complexes associated with tethering containing helical rods) family which comprises the exocyst, COG, GARP, and DSL1 complexes and share a similar structure organisation with an N-terminal coiled-coil and a C-terminal α-helical bundle, which might be a protein-protein interaction module necessary for the formation of functional complexes.RINT-1 interacts with Rad50 only during late S and G2/M phases and participates in radiation induced checkpoint control [ ]. RINT-1 also functions in membrane trafficking from the endoplasmic reticulum (ER) to the Golgi complex in interphase cells [, , ].Tip20 is involved in the retrograde transport from the Golgi to the ER [ , ].Arabidopsis Mag2 functions in the transport of storage protein precursors between the ER and Golgi complex in plants [ , ].
Short Name  RINT1_Tip20

0 Child Features

2 Gene Families

315 Genes

3 Ontology Annotations

0 Parent Features

14 Publications

USDA
InterMine logo
The Legume Information System (LIS) is a research project of the USDA-ARS:Corn Insects and Crop Genetics Research in Ames, IA.
LegumeMine || ArachisMine | CicerMine | GlycineMine | LensMine | LupinusMine | PhaseolusMine | VignaMine | MedicagoMine
InterMine © 2002 - 2022 Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom