Protein Domain : Arsenical pump membrane protein, ArsB IPR000802

Type  Family
Description  Arsenic is a toxic metalloid whose trivalent and pentavalent ions inhibit a variety of biochemical processes. Operons that encode arsenic resistancehave been found in multicopy plasmids from both Gram-positive and Gram-negative bacteria []. The resistance mechanism is encoded from a singleoperon, which houses an anion pump. The pump has two polypeptide components:a catalytic subunit (the ArsA protein), which functions as an oxyanion-stimulated ATPase; and an arsenite export component (the ArsB protein),which is associated with the inner membrane [ ]. The ArsA and ArsB proteinsare thought to form a membrane complex that functions as an anion-translocating ATPase.The ArsB protein is distinguished by its overall hydrophobic character, in keeping with its role as a membrane-associated channel. Sequenceanalysis reveals the presence of 13 putative transmembrane (TM) regions.
Short Name  Arsenical_pump_ArsB

0 Child Features

0 Gene Families

58 Genes

3 Ontology Annotations

0 Parent Features

12 Publications

USDA
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