v5.1.0.3
Glycine data from LIS
Type | Family |
Description | This group represents a clathrin heavy chain.Clathrin is a triskelion-shaped cytoplasmic protein that polymerises into a polyhedral lattice on intracellular membranes to form protein-coated membrane vesicles. Lattice formation induces the sorting of membrane proteins during endocytosis and organelle biogenesis by interacting with membrane-associated adaptor molecules. Clathrin consists of three heavy chain subunits, which are the main structural component of the clathrin vesicle coat, and three light chain molecules that interact with the heavy chains to self-assemble into a three-legged triskelion structure. Each leg consists of one heavy chain and one light chain. The clathrin heavy-chain contains a 145-residue repeat that is present in seven copies [, ]. |
Short Name | Clathrin_heavy_chain |