v5.1.0.3
Glycine data from LIS
Description | This family contains sequences expressed in eukaryotic organisms bearing high similarity to the WAPL conserved region of D. melanogaster wings apart-like protein. This protein is involved in the regulation of heterochromatin structure [1]. hWAPL (Swiss:Q7Z5K2), the human homologue, is found to play a role in the development of cervical carcinogenesis, and is thought to have similar functions to Drosophila wapl protein [2]. Malfunction of the hWAPL pathway is thought to activate an apoptotic pathway that consequently leads to cell death [2]. |
Namespace | Family |