Ontology Term : Pfam:PF00368 Hydroxymethylglutaryl-coenzyme A reductase EMBL-EBI
Description  The HMG-CoA reductases catalyse the conversion of HMG-CoA to mevalonate, which is the rate-limiting step in the synthesis of isoprenoids like cholesterol. Probably because of the critical role of this enzyme in cholesterol homeostasis, mammalian HMG-CoA reductase is heavily regulated at the transcriptional, translational, and post-translational levels [2].
Namespace  Family
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