v5.1.0.3
Glycine data from LIS
Type | Homologous_superfamily |
Description | Translins are DNA-binding proteins that specifically recognise consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. They seem to recognise single-sranded DNA ends generated by staggered breaks occuring at recombination hot spots [ ].Translin folds into an α-α superhelix, consisting of two curved layers of alpha/alpha topology [ , ]. This structure can be divided into two α-bundle subdomains. This entry represents the N-terminal alpha bundle subdomain. |
Short Name | Translin_N |