Protein Domain : Inositol-tetrakisphosphate 1-kinase IPR008656

Type  Family
Description  This entry represents inositol-tetrakisphosphate 1-kinase, which is also called inositol 1,3,4-trisphosphate 5/6-kinase.Inositol-tetrakisphosphate 1-kinase can phosphorylate various inositol polyphosphates, such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Phosphorylation of Ins(3,4,5,6)P4 at position 1 forms Ins(1,3,4,5,6)P5 which has regulatory importance, since Ins(3,4,5,6)P4 is an inhibitor of plasma membrane Ca(2+)-activated Cl(-) channels. Phosphorylation of Ins(1,3,4)P3 on O-5 and O-6 forms Ins(1,3,4,6)P4, an essential molecule in the hexakisphosphate (InsP6) pathway [ , , , , ].
Short Name  Inositol_tetrakis-P_1-kinase

0 Child Features

3 Gene Families

560 Genes

6 Ontology Annotations

0 Parent Features

14 Publications

USDA
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