Protein Domain : Transcription factor TFIIH subunit p52/Tfb2 IPR004598

Type  Family
Description  This entry represents the p52/Tfb2 subunit in the TFIIH complex, which is not only required for transcription but also plays a central role in DNA repair. The TFIIH multiprotein complex consists of a 7-subunit core (XPB, p62, p52, p44, p34, and TTDA) that is associated with a 3-subunit CDK-activating kinase module (MAT1, cyclin H and Cdk7) [ , , ]. The p52 subunit interacts with subunit XPB, which is an ATP-dependent 3'-5' DNA helicase, and stimulates its ATPase activity [].
Short Name  TFIIH_p52/Tfb2
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0 Child Features

1 Gene Families

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242 Genes

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3 Ontology Annotations

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14 Publications

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