Protein Domain : Wings apart-like protein, C-terminal IPR022771

Type  Domain
Description  This entry represents the conserved region of D. melanogaster wings apart-like protein, WAPL. It is involved in the regulation of heterochromatin structure [ ]. hWAPL (), the human homologue, is found to play a role in the development of cervical carcinogenesis, and is thought to have similar functions to Drosophila wapl protein [ ]. Malfunction of the hWAPL pathway is thought to activate an apoptotic pathway that consequently leads to cell death [].The WAPL-like proteins can be found in metazoa, fungi and plants.
Short Name  WAPL_C

0 Child Features

2 Gene Families

124 Genes

0 Ontology Annotations

0 Parent Features

14 Publications

USDA
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