Protein Domain : MIF4G-like, type 3 IPR003890

Type  Domain
Description  MIF4G stands for middle domain of eukaryotic initiation factor 4G (eIF4G). eIF4G is a component of the translation initiation factor eIF4F complex and the cytoplasmic cap-binding protein complex (CBC). In the cytoplasm, cap binding complexes, distinct in their composition from nuclear cap-binding complexes, have important roles in the initiation of mRNA translation.The MIF4G domain also occurs in other proteins, including CBP80, a component of the nuclear CBC and NMD2, involved in the cytoplasmic nonsense-mediated mRNA decay. The domain is rich in α-helices and may contain multiple α-helical repeats. In eIF4G, this domain binds to the two other components of the eIF4F complex, eIF4A and eIF3E, and to RNA and DNA [ ].
Short Name  MIF4G-like_typ-3

0 Child Features

0 Gene Families

929 Genes

2 Ontology Annotations

0 Parent Features

13 Publications

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