Protein Domain : CDC48, domain 2 IPR004201

Type  Domain
Description  The CDC48 N-terminal domain is a protein domain found in AAA ATPases including cell division protein 48 (CDC48), VCP-like ATPase (VAT) and N-ethylmaleimide sensitive fusion protein. It is a substrate recognition domain which binds polypeptides, prevents protein aggregation, and catalyses refolding of permissive substrates. It is composed of two equally sized subdomains. The amino-terminal subdomain forms a double-psi β-barrel whose pseudo-twofold symmetry is mirrored by an internal sequence repeat of 42 residues. The carboxy-terminal subdomain forms a novel six-stranded β-clamp fold [ ]. Together these subdomains form a kidney-shaped structure. This entry represents the carboxy-terminal subdomain.
Short Name  Cdc48_dom2

0 Child Features

1 Gene Families

558 Genes

0 Ontology Annotations

0 Parent Features

14 Publications

USDA
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