Protein Domain : Solute carrier family 13 IPR001898

Type  Family
Description  Integral membrane proteins that mediate the intake of a wide variety of molecules with the concomitant uptake of sodium ions (sodium symporters) canbe grouped, on the basis of sequence and functional similarities into a number of distinct families. The SLC13 family consists mainly of dicarboxylate and sulfate transporters [, ], and includes of the following proteins:Mammalian sodium/sulphate cotransporter [ ].Mammalian renal sodium/dicarboxylate cotransporter [ ], which transports succinate and citrate.Mammalian sodium/citrate cotransporter [ ], which mediates the entry of citrate into cells, which is a critical participant of biochemical pathways [, ].Mammalian intestinal sodium/dicarboxylate cotransporter.Chlamydomonas reinhardtii putative sulphur deprivation response regulator SAC1 [ ].These transporters are proteins of from 430 to 620 amino acids which are highly hydrophobic and which probably contain about 12 transmembrane regions.
Short Name  SLC13A/DASS

1 Child Features

4 Gene Families

608 Genes

3 Ontology Annotations

0 Parent Features

14 Publications

USDA
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