Protein Domain : Recombination protein RecR, conserved site IPR015967

Type  Conserved_site
Description  The bacterial protein RecR is an important regulator in the RecFOR homologous recombination pathway during DNA repair [ , , , ]. It acts with RecF and RecO forming a complex that facilitates the loading of RecA onto ssDNA [, ]. RecR is a zinc metalloprotein consisting of a N-terminal helix-hairpin-helix (HhH) motif, a middle region containing a zinc finger motif and a Toprim domain, and a C-terminal domain comprising a divergent Walker B motif and a C-terminal helix [, ]. This conserved site represents the C4-type zinc finger which contains four strictly conserved cysteine residues that coordinates a zinc ion. Mutations in this domain affects bacterial survival suggesting that it plays an important role, likely in DNA binding [ ].
Short Name  Rcmb_RecR_CS

0 Child Features

0 Gene Families

99 Genes

3 Ontology Annotations

0 Parent Features

13 Publications

USDA
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