v5.1.0.3
Glycine data from LIS
Description | DEK is a chromatin associated protein that is linked with cancers and autoimmune disease. This domain is found at the C terminal of DEK and is of clinical importance since it can reverse the characteristic abnormal DNA-mutagen sensitivity in fibroblasts from ataxia-telangiectasia (A-T) patients [3]. The structure of this domain shows it to be homologous to the E2F/DP transcription factor family [1]. This domain is also found in chitin synthase proteins like Swiss:Q8TF96, and in protein phosphastases such as Swiss:Q6NN85. |
Namespace | Domain |