Ontology Term : Pfam:PF07777 G-box binding protein MFMR EMBL-EBI

Description  This region is found to the N-terminus of the Pfam:PF00170 transcription factor domain. It is between 150 and 200 amino acids in length. The N-terminal half is rather rich in proline residues and has been termed the PRD (proline rich domain) [2], whereas the C-terminal half is more polar and has been called the MFMR (multifunctional mosaic region). It has been suggested that this family is composed of three sub-families called A, B and C [1], classified according to motif composition. It has been suggested that some of these motifs may be involved in mediating protein-protein interactions [1]. The MFMR region contains a nuclear localisation signal in bZIP opaque and GBF-2 [2]. The MFMR also contains a transregulatory activity in TAF-1. The MFMR in CPRF-2 contains cytoplasmic retention signals [2].
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