Protein Domain : SNF2, N-terminal IPR000330

Type  Domain
Description  This domain is found in proteins involved in a variety of processes including transcription regulation (e.g., SNF2, STH1, brahma, MOT1), DNA repair (e.g., ERCC6, RAD16, RAD5), DNA recombination (e.g., RAD54), and chromatin unwinding (e.g., ISWI) as well as a variety of other proteins with little functional information (e.g., lodestar, ETL1) [ , , ]. SNF2 functions as the ATPase component of the SNF2/SWI multisubunit complex, which utilises energy derived from ATP hydrolysis to disrupt histone-DNA interactions, resulting in the increased accessibility of DNA to transcription factors [].Proteins that contain this domain appear to be distantly related to the DEAX box helicases.
Short Name  SNF2_N

5 Child Features

28 Gene Families

4577 Genes

1 Ontology Annotations

1 Parent Features

14 Publications

USDA
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