Protein Domain : RNA recognition motif domain, eukaryote IPR003954

Type  Domain
Description  Many eukaryotic proteins that are known or supposed to bind single-stranded RNA contain one or more copies of a putative RNA-binding domain of about 90 amino acids. This is known as the eukaryotic putative RNA-binding region RNP-1 motif [ , ], or RNA recognition motif (RRM). RRMs are found in a variety of RNA binding proteins, including heterogeneous nuclear ribonucleoproteins (hnRNPs), proteins implicated in regulation of alternative splicing, and protein components of small nuclear ribonucleoproteins (snRNPs). The motif also appears in a few single stranded DNA binding proteins. The RRM structure consists of four strands and two helices arranged in an α/β sandwich, with a third helix present during RNA binding in some cases [].
Short Name  RRM_dom_euk

3 Child Features

0 Gene Families

1000 Genes

1 Ontology Annotations

1 Parent Features

13 Publications

USDA
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