Protein Domain : FKBP-type peptidyl-prolyl cis-trans isomerase domain IPR001179

Type  Domain
Description  FKBP-type peptidylprolyl isomerases ( ) in vertebrates, are receptors for the two immunosuppressants, FK506 and rapamycin. The drugs inhibit T cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. Peptidylprolyl isomerases accelerate protein folding by catalysing the cis-trans isomerisation of proline imidic peptide bonds in oligopeptides. These proteins are found in a variety of organisms [ ].This entry represents a domain found in FKBP-type peptidylprolyl isomerases.
Short Name  PPIase_FKBP_dom

0 Child Features

22 Gene Families

1000 Genes

1 Ontology Annotations

0 Parent Features

14 Publications

USDA
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