Protein Domain : Knottin, scorpion toxin-like IPR003614

Type	Domain
Description	Knottins are small proteins characterised by a cystine-knot [ ]. They constitute a large family of structurally related peptides with diverse biological functions, including inhibitors, anti-microbial peptides and toxins [].The scorpion toxin-like domain is found in a subgroup of metazoan knottins mainly from the arthropoda, which include the antibacterial defensins [ ] and the scorpion alpha and beta-neurotoxins [, ]. The plant sequences include members of the gamma-thionin family, which are plant defensins that have no antifungal activity. Other members are insect alpha-amylase inhibitors, cysteine-rich antifungal proteins and proteins annotated as proteinase inhibitors; those that are characterised belong to MEROPS inhibitor family I18, clan I.
Short Name	Scorpion_toxin-like