Protein Domain : TRAM/LAG1/CLN8 homology domain IPR006634

Type  Domain
Description  TLC is a protein domain with at least 5 transmembrane α-helices. Lag1p and Lac1p are essential foracyl-CoA-dependent ceramide synthesis [ ], TRAM is a subunitof the translocon and the CLN8 gene is mutated in Northern epilepsy syndrome. Proteins containing this domain may possessmultiple functions such as lipid trafficking, metabolism, or sensing. Trh homologues possess additionalhomeobox domains [ ].
Short Name  TLC-dom

0 Child Features

5 Gene Families

1000 Genes

1 Ontology Annotations

0 Parent Features

14 Publications

USDA
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