Protein Domain : Glutamate dehydrogenase IPR014362

Type	Family
Description	This entry represents glutamate dehydrogenases (GDH). The tertiary structure have been solved for the GDHs from Thermotoga maritima and Pyrococcus furiosus, both of which are thermostable because of an ion-pair network in the hinge region [ ]. Some GDHs are NADP-specific, such as GdhA from Escherichia coli, which catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia [, ]. In eukaryotes, NADP-dependent GDHs may be mitochondrial, such as GluD from Dictyostelium discoideum [].
Short Name	Glu_DH