Protein Domain : GDP-fucose protein O-fucosyltransferase IPR019378

Type  Family
Description  This is a family of conserved proteins representing the enzyme responsible for adding O-fucose to EGF (epidermal growth factor-like) repeats. Six highly conserved cysteines are present as well as a DXD-like motif (ERD), conserved in mammals, Drosophila, and Caenorhabditis elegans. Both features are characteristic of several glycosyltransferase families. The enzyme is a membrane-bound protein released by proteolysis and, as for most glycosyltransferases, is strongly activated by manganese [ ].
Short Name  GDP-Fuc_O-FucTrfase

4 Child Features

28 Gene Families

4577 Genes

0 Ontology Annotations

0 Parent Features

14 Publications

USDA
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