Protein Domain : RNA polymerases, subunit N, zinc binding site IPR020789

Type	Binding_site
Description	In eukaryotes, there are three different forms of DNA-dependent RNA polymerases ( ) transcribing different sets of genes. Each class of RNA polymerase is an assemblage of ten to twelve different polypeptides. In archaebacteria, there is generally a single form of RNA polymerase which also consists of an oligomeric assemblage of 10 to 13 polypeptides. Archaebacterial subunit N (gene rpoN) [] is a small protein of about 8kDa, itis evolutionary related [ ] to a 8.3kDa component shared by all three forms ofeukaryotic RNA polymerases (gene RPB10 in yeast and POLR2J in mammals) as well as to African swine fever virus (ASFV) protein CP80R [].This signature spans the conserved region, which is located at the N-terminal extremity of these polymerase subunits; this region contains twocysteines that binds a zinc ion [ ].
Short Name	RNA_pol_suN_Zn-BS