Protein Domain : Serine incorporator/TMS membrane protein IPR005016

Type  Family
Description  The serine incorporator/TMS membrane protein (TDE1/TMS) family include SERINC1-5 from mammals and membrane protein Tms1 from budding yeasts. Members in this family contain eleven transmembrane helices. SERINC1-5 function in incorporating serine into membranes and facilitating the synthesis of two serine-derived lipids, phosphatidylserine and sphingolipids [ ]. Serinc3 (also known as TDE1) is overexpressed in tumours []. The function of Tms1 is not clear.
Short Name  TDE1/TMS
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0 Child Features

5 Gene Families

Trail: ProteinDomain

510 Genes

Trail: ProteinDomain

1 Ontology Annotations

Trail: ProteinDomain

0 Parent Features

14 Publications

Trail: ProteinDomain
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