Protein Domain : Nicotinate phosphoribosyltransferase family IPR007229

Type	Family
Description	Nicotinate phosphoribosyltransferase ( ) is the rate-limiting enzyme that catalyses the first reaction in the NAD salvage synthesis [ ]. Members in this family can be split into two further subfamilies represented in and . Members in have a different (longer) spacing of several key motifs and have an additional C-terminal domain of up to 100 residues. However, one argument suggesting that this family represents the same enzyme is that no species has a member of both subfamilies. Another is that the gene encoding this protein is located near other NAD salvage biosynthesis genes in Nostoc and in at least four different Gram-positive bacteria.
Short Name	Nic_PRibTrfase-Fam