Protein Domain : Thiamine pyrophosphate enzyme, TPP-binding IPR011766

Type	Domain
Description	A number of enzymes require thiamine pyrophosphate (TPP) (vitamin B1) as a cofactor. It has been shown [ ] that some of these enzymes are structurally related. The thiamin diphosphate-binding fold comprises two different functional modules, the pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules. This represents the TPP binding domain which localizes at the C-terminal of TPP enzymes and in some members has been described as the PP-binding module.
Short Name	TPP_enzyme_TPP-bd