Protein Domain : Transketolase, bacterial-like IPR005478

Type	Family
Description	Transketolase ( ) (TK) catalyzes the reversible transfer of a two-carbon ketol unit from xylulose 5-phosphate to an aldose receptor, such as ribose 5-phosphate, to form sedoheptulose 7-phosphate and glyceraldehyde 3- phosphate. Thisenzyme, together with transaldolase, provides a link between the glycolytic and pentose-phosphate pathways. TK requires thiamine pyrophosphate as a cofactor. This group includes two proteins from the yeast Saccharomyces cerevisiae (Baker's yeast) but excludes dihydroxyactetone synthases(formaldehyde transketolases) from various yeasts and the even more distant mammalian transketolases. Among the family of thiamine diphosphate-dependent enzymes that includestransketolases, dihydroxyacetone synthases, pyruvate dehydrogenase E1-beta subunits, and deoxyxylulose-5-phosphate synthases, mammalian and bacterial transketolases seem not tobe orthologous.
Short Name	Transketolase_bac-like