Protein Domain : SCAR/WAVE family IPR028288

Type  Family
Description  This entry represents the SCAR/WAVE family. Members in this family include actin-binding protein WASF1-3 (WAVE 1-3), protein SCAR 1-4, protein WAVE5 and SCAR-like proteins.SCAR/WAVE family members are downstream effector molecules receiving information from multiple signalling pathways and responding by promoting the actin nucleating activity of the ubiquitous Arp2/3 complex [ ]. They are part of the WAVE complex that regulates lamellipodia formation in animals and maintains cell shape in plants [, , ]. WAVE1 is also involved in the regulation of mitochondrial dynamics [].
Short Name  SCAR/WAVE_fam

0 Child Features

3 Gene Families

365 Genes

2 Ontology Annotations

0 Parent Features

14 Publications

USDA
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